Abstract: The subject of this research is the organization of regulatory, financial and infrastructure support of cluster projects of the Siberian Federal District (SFD). The object of this research is the projects of innovative clusters of SFD subjects, which comprise a group of pilot clusters of the Russian Federation or clusters that are leaders in the world-class investment attractiveness. The authors meticulously examine the existing government measures of organizational, regulatory, financial and infrastructure support of cluster projects, centers of cluster development, external organizations that provide infrastructure support, as well as presence of infrastructure themes of projects of the SFD cluster formations themselves. Special attention is given to the systematization, analysis and determination of differences in provision of the SFD subjects with organizational, regulatory, financial and infrastructure support of execution of cluster projects. A conclusion is made that there is sufficient existing organizational, regulatory and infrastructure support of execution of the cluster projects. The author’s special contribution into the research of this topic consists in structuring and generalization of information regarding the existing organizational, regulatory and infrastructure support of cluster projects of the examined SFD subjects, and formulation of differences of the level of the provided support based on the analysis of the acquired data. The novelty of this work lies in systematization of the organizational, regulatory and infrastructure support of cluster project of the SFD subjects and formulation of results of the comparative analysis of the level of the provided support.