Abstract: The paper presents the results of an experimental study aimed at identifying psychophysiological predictors of learning success among students of grades 1-11 of secondary schools. The study involved 611 children and adolescents aged 7 to 18 years. The results of sensorimotor tests of varying complexity were analyzed, assessing the reaction time to auditory and visual stimuli. The results of the parents' questionnaire were also taken into account. It is shown that only complex sensorimotor tests, during which the child must respond to targeted combinations of visual stimuli, ignoring all other stimuli, have predictive significance that allows predicting the success of a child in learning.   Previously, the same results were obtained by us for elementary school students. The present study allowed us to establish that complex sensorimotor tests predict success in learning throughout the entire period of schooling from grades 1 to 11. Children who showed high results in complex sensorimotor tests significantly study better, and their parents believe that school grades correspond to the abilities of children. It was also found that girls study better, and the use of gadgets for more than one hour a day has a negative impact on the success of children in learning.